Based on sensitivity distribution and the definition of margin of firing reliability for initiating explosive devices given in GJB376, the quantitative relationship between producer risk and margin of firing reliability of initiating explosive devices was deduced. According to the relationship and up-and-down method test data, the margin of firing reliability and producer risk of a stab detonator are 1.74 and 0.003% respectively, and the margin of firing reliability and producer risk of an electronic detonator are 1.48 and 0.00096% respectively. Results show that the quantitative relationship between producer risk and margin of firing reliability of initiating explosive devices is accordant with practical products.