Lead 5-(2,4-dinitroanilino)-salicylate (DNAS-Pb) was synthesized with yield of 70% by using 2,4-dinitrobenzyl chloride, 5-aminosalicylic acid and lead nitrate as raw materials. Its chemical structure was characterized by FT-IR spectra, MS, X-ray fluorescence diffraction and elementary analysis. The catalysis of DNAS-Pb on the combustion of double-base propellant was investigated. The results show that DNAS-Pb possesses good catalytic effect, and markedly increases the burning rate and makes the propellant produce plateau combustion and mesa combustion. The plateau zone extends from 6 MPa to 10 MPa, and the burning rate is approximately 13.2 mm·s^-1 and the pressure exponent is 0.03. The mesa zone extends from 10 MPa to 14 MPa.