Using a laser monitoring observation technique, the solubility of RDX in cyclohexanone,dimethylsulfoxide, γ-butyrolactone, N-methyl-2-pyrrolidone and N,N-dimethylformamide was determined. The Apelblat equation, λh equation and NRTL equation were used to correlate the solubility data. The results show that the Apelblat equation could best correlate the solid-liquid equilibrium data, the corresponding averge relative deviations are between 0.1% and 2.18%. For the solubility curves, the selection of appropriate polynomial and the parameter fitting were conducted, the relative deviations were less than 1%.