LS-DYNA software was employed to investigate the asymmetric collision of detonation wave, empennage formation and velocity of explosively formed projectile(EFP) which are caused by three-point initiation synchronization error. Meanwhile, the distortion characters of the liner formed by the composite detonation waves were analyzed. Results indicate that the deviation of trigeminal high-pressure and central ultrahigh-pressure area from liner center are attributed to the error of three-point initiation, which lead to the irregularly formation of EFP empennage. It is noted that a better empennage formation can be obtained when the synchronization error is less than 100 ns. In addition, it will decrease the velocity in the horizontal direction and increase the flight stability of EFP with fins when the middle initiation point synchronization error is about half of the max.