In order to investigate the reaction characteristics of oxidizer-fuel composite materials with different particle sizes in constant-volume combustion， laser ignition and detonation environment of high energy explosive hexanitrohexaazaisowurtzitane （CL-20）， three particle sizes of perfluoropolyether-functionalized micro/nano aluminum （nAl_150@xPFPE， μAl_1@xPFPE and μAl_5@xPFPE， where x=2.5%， 5.0%， 7.5%） was constructed by particle suspension method， and CL-20 based aluminized explosive was prepared by kneading granulation method. The pressure-time curve， laser-induced ignition process， energy release rate and efficiency of samples in CL-20 were studied by means of closed constant-volume explosive device， laser ignition， detonation velocity and detonation heat test equipment， respectively. The results showed that with the increase of PFPE mass fraction， the peak pressure and pressurization rate of nAl_150@xPFPE samples and μAl_1@xPFPE samples increased gradually， while the peak pressure of μAl_1@7.5%PFPE sample reached 4138.4 kPa and its pressurization rate reached 0.216 MPa·ms^-1. However， when the PFPE mass fraction exceeded 5.0%， the pressurization rate seemed to slow down. At the same time， with the increase of PFPE mass fraction， the burning rate of PFPE-functionalized micro/nano aluminum in CL-20 increased gradually. When x=7.5%， the burning rate of all the three samples with different particle sizes in CL-20 increased by 2.1 cm·s^-1， 1.8 cm·s^-1 and 2.3 cm·s^-1， respectively. In addition， four kinds of fuel-rich CL-20 based aluminized explosives were designed. Among them， the measured detonation velocity of JWL-3 explosive （62% CL-20/32% μAl_1@5.0%PFPE/6% binder） was 8125 m·s^-1， the measured detonation heat was 8049.8 kJ·kg^-1， and the energy release efficiency reached 86.10% （measured by detonation heat）.