The fast-running method based on engineering experience is an important tool to assess the explosion damage inside the building structure. To provide the reference for the selection and subsequent improvement of relevant calculation methods， the full-scale confined explosion tests on three-story masonry-concrete building were carried out under two scenarios. The five fast-running methods developed in recent years （i.e. FIST method， charge weight-standoff graphs method， equivalent dynamic load method， energy method， equivalent method） were used to calculate the damage of the buildings. The evaluation indicator and scoring criteria of 5-dimensional calculation ability were put forward. The characteristics of each fast-running method were compared and analyzed. The reasons for the difference in the ability of each method are discussed. Some suggestions for improvement are given. The results show that the charge weight-standoff graphs method is not suitable for the damage assessment of building structure subjected to confined explosions. The FIST method and equivalent method have high accuracy in calculating the masonry wall. The energy method has high accuracy in calculating the RC slabs， but the computational efficiency is low. The calculation efficiency of equivalent dynamic load method is high， but the calculation accuracy is low. In addition， considering the propagation law of the shock wave in complex building structure， improving the scale of numerical simulation are the main way to improve the computing ability of FIST-like and equivalent-like method.